关键词:
DNA分子
纳米孔
操纵
易位
传感器精度
DNA测序
延缓
纳米技术
摘要:
Nanopores are emerging sensitive sensors that can detect and analyze single charged *** present a promising approach for sequencing human genome below US$1,000 because of its superior performance,such as high throughput and low ***,a dominant bottleneck,that is,the high translocation speed of DNA molecules,has to be *** property decreases accuracy of nanopore sensors to the single-base *** this review,we mainly introduce the recent research works of retarding and manipulating of DNA motion through nanopores by actively control of three forces,which are the driving force,interaction force between nanopore and molecule,and exterior drag ***,conclusion and further outlook are presented on future directions of nanopore-based DNA sequencing technology.